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diabetes in pregnancy: management in labour


Diabetes in Pregnancy: Management in Labour CPG


Obstetric management


The standard management of labour for a 'high risk' pregnancy applies to women with diabetes, and includes the following special considerations:
  • Continuous electronic fetal monitoring is recommended although may not be necessary for women with uncomplicated gestational diabetes (GDM) in spontaneous labour
  • Labour should not be prolonged
  • The paediatric registrar should be notified of impending delivery
  • Delivery should be supervised by an experienced accoucheur (Senior midwife or Obstetric registrar)

Glycaemic control


Pre-induction


  • Usual insulin while having prostaglandin
  • Usual insulin dose night prior to planned amniotomy (ARM)
  • Morning of ARM - fasting glucose level, light breakfast, adjust usual short-acting insulin according to fasting glucose level and breakfast

Birthing suite


Oral food and fluids at discretion of Birthing Suite staff


Monitoring


Urine


  • Test for ketones. If ketones are present at a moderate or high level, consider hydration and contact Diabetes Nurse Educator (DNE) (or Diabetes Physician if DNE is not available)
  • Test for protein

Blood glucose monitoring


  • Type 1 and Type 2 and GDM on insulin 2-hourly
  • GDM not on insulin 4-hourly

Intravenous therapy


  • Not routinely required for diabetes management
  • Normal Saline should be used if requires IV therapy, no need for routine IV Dextrose
  • Caution with fluid overload in severe pre-eclampsia

Insulin


Sliding scale - all 2-hourly

LOW DOSE
  • For Type 1 diabetes and women with GDM on insulin receiving < 40 units/day antenatally

Blood glucose level (mm/l/L)


NovoRapid S/C (Humalog if patient using this already)


0-5
nil
5.1-7.0
2 units
7.1-10.0
4 units
10.1-13.0
6 units
>13
8 units and call RMO

HIGH DOSE
  • For Type 2 diabetes and women with GDM on insulin receiving > or= to 40 Units/day antenatally

Blood glucose level (mm/l/L)


NovoRapid S/C (Humalog if patient using this already)


0-5
nil
5.1-7.0
4 units
7.1-10.0
6 units
10.1-13.0
8 units
>13
10 units and call RMO

Intravenous insulin infusion
  • Suitable for patients requiring intensive therapy and/or poor control on a sliding scale, for example severe preeclampsia. Consult with Diabetes Physician.
  • Via syringe pump
  • 50 units NovoRapid insulin in 50 mLs of Normal saline

  • Aim to keep blood glucose level 4-7mmol/L
  • Start rate of 1-2 units/hour depending on initial blood glucose level
  • If blood glucose level > 7 mmol/l, increase insulin by 1 unit/hour
  • If blood glucose level < 4 mmol/l, decrease insulin by 1 unit/hour
  • If blood glucose level 4-7 mmol/L, maintain rate.

NOTE: DO NOT USE THIS REGIMEN FOR DIABETIC KETOACIDOSIS
  • Consult Endocrinologist on call for all patients with DIABETIC KETOACIDOSIS


Management of hypoglycaemia


  • Treat orally if possible

Elective caesarean section


  • Usual insulin the night before Caesarean section
  • Book first on the theatre list in the morning
  • Morning of Caesarean section - withold usual insulin
  • Measure blood glucose level in theatre prior to anaesthetic
  • Avoid IV Dextrose unless hypoglycaemic
  • Postoperatively use low-dose sliding scale
  • 0700: 1200: 1700: 2200: until oral intake established,
  • then, fasting and before each meal.

Postpartum


Insulin requirements fall dramatically postpartum

Monitor glucose levels to avoid profound and/or prolonged hypoglycaemia. Management of Hypoglycaemia (clinical algorithim)

Type 1 and Type 2
  • Blood glucose monitoring within 2 hours of birth then
  • QID: Fasting and before each meal
  • Sliding Scale insulin (low dose)
  • Regular review by Diabetes Clinical Nurse Consultant and Physician until discharge.
  • Type 2 will usually not require insulin in the postnatal period unless blood glucose levels are consistently elevated.
  • Oral hypoglycaemic agents are not recommended while breastfeeding.

GDM
  • Blood glucose monitoring B.D. for 48 hours
  • Insulin is ceased post delivery
  • If blood glucose levels > 7.0 mmol/L, continue to monitor until discharge - fasting and 2 hours after meals
  • If blood glucose levels are persistently elevated after 72 hours, contact Diabetes Clinical Nurse Consultant


Neonatal Management


Commence feeding within one hour of birth and feed 3 - 4 hourly.

Measure Blood Sugar Level (BSL):
  • at four hours of age or before the second feed (whichever comes first)
  • immediately if clinical signs of hypoglycaemia present
  • before each subsequent feed until 3 consecutive readings ≥ 2.6 mmol/L or as requested by paediatric registrar.

Recommence glucose monitoring if change in feeding or clinical condition.

Transfer infant of a mother who has diabetes to SCN if:
a. Maternal indications:
  • poor control during pregnancy (most recent HbA1c > 7.5%)
  • BSL > 8 mmol/L during labour
  • IV glucose during labour

b. Infant indications:
  • unwell (e.g. signs of respiratory distress)
  • macrosomic (> 90th centile)
  • small for gestational age infants (< 10th centile), low birthweight infants (< 2,500gm) or clinically wasted regardless of birthweight
  • preterm (< 37 weeks gestation)
  • other reason(s) for SCN admission.

All other well infants of mothers who have diabetes (type 1, type 2 or gestational diabetes, controlled by insulin or diet) should be transferred to the postnatal ward with their mother. Refer to Management of Infants at Risk for Hypoglycaemia in Birth Suites and Postnatal Wards and flowchart 1 in the Women's procedure: Hypoglycaemia Infant Management (intranet access only).

Note: Mother managed with insulin prior to or during pregnancy is not an indication alone for transfer of infant to SCN.

References


Refer to the Women's procedure: Hypoglycaemia Infant Management (intranet access only)
Refer to NETS Neonatal Handbook: Management Neonatal Hypoglycaemia


22 April 2008

Royal Women's Hospital Clinical Practice Guidelines (CPGs) are intended to provide guidance to health care professionals, based on a thorough evaluation of research evidence, on the practical assessment and management of specific clinical issues or situations. The guidelines allow some flexibility on the part of the health care professional based on the needs of the specific patient for whom they are caring.

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