evidence table: hyperglycaemia: management of preterm infants in neonatal intensive care

Evidence Table: Hyperglycaemia: Management of Preterm Infants in Neonatal Intensive Care

Refer to the Women's Clinical Practice Guideline: Hyperglycaemia: Management of Preterm Infants in Neonatal Intensive Care.

Author Title Source Level of Evidence (I-IV) Comments 1. Mericq V. Prematurity and insulin sensitivity. Hormone Research 2006;65 Suppl 3:131-6. III-3 review 2. Mitanchez-Mokhtari D, Lahlou N, Kieffer F, Magny JF, Roger M, Voyer M. Both relative insulin resistance and defective islet beta-cell processing of proinsulin are responsible for transient hyperglycemia in extremely preterm infants. Pediatrics 2004;113:537-41. III-2 Prospective comparative 3. Hall NJ, Peters M, Eaton S, Pierro A. Hyperglycemia is associated with increased morbidity and mortality rates in neonates with necrotizing enterocolitis. Journal of Pediatric Surgery 2004;39:898-901 III-2 cohort 4. Hays SP, Smith EOB, Sunehag AL. Hyperglycemia Is a Risk Factor for Early Death and Morbidity in Extremely Low Birth-Weight Infants. Pediatrics 2006;118:1811-8. III-2 cohort 5. Manzoni P, Castagnola E, Mostert M, Sala U, Galletto P, Gomirato G. Hyperglycaemia as a possible marker of invasive fungal infection in preterm neonates. Acta Paediatrica 2006;95:486-93. III-2 Case control 6. Van den Berghe G, Wouters PJ, Bouillon R, et al. Outcome benefit of intensive insulin therapy in the critically ill: Insulin dose versus glycemic control. Crit Care Med 2003;31:359-66. II Prospective randomised 7. Alsweiler JM, Kuschel CA, Bloomfield FH. Survey of the management of neonatal hyperglycaemia in Australasia. Journal of Paediatrics and Child Health 2007;43:632-5. survey 8. Ogilvy-Stuart AL, Midgley P. Practical Neonatal Endocrinology Cambridge University Press; 2006. text 9. Hey E. Hyperglycaemia and the very preterm baby Seminars in Fetal and Neonatal Medicine 2005;10:377-87. III-2 cohort 10. Coulthard MG, Hey EN Renal processing of glucose in well and sick neonates. Archives of Disease in Childhood Fetal & Neonatal Edition 1999;81:F92-8. III-2 cohort 11. Hewson M, Nawadra V, Oliver J, Odgers C, Plummer J, Simmer K. Insulin infusions in the neonatal unit: delivery variation due to adsorption. Journal of Paediatrics & Child Health 2000;36:216-20. In-vitro 12. Fuloria M, Friedberg MA, DuRant RH, Aschner JL. Effect of Flow Rate and Insulin Priming on the Recovery of Insulin From Microbore Infusion Tubing. Pediatrics 1998;102:1401-6. In-vitro

Published: 13 January 2009

Royal Women's Hospital Clinical Practice Guidelines (CPGs) are intended to provide guidance to health care professionals, based on a thorough evaluation of research evidence, on the practical assessment and management of specific clinical issues or situations. The guidelines allow some flexibility on the part of the health care professional based on the needs of the specific patient for whom they are caring.

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