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gbs colonisation: antenatal/intrapartum strategies to prevent early-onset neonatal sepsis


GBS Colonisation: Antenatal/Intrapartum Strategies to Prevent Early-Onset Neonatal Sepsis CPG

Group B Streptococcus infection in the neonate is associated with high rates of morbidity and mortality. Chemoprophylaxis of the pregnant woman will prevent or reduce this risk factor.




Algorithm


Refer GBS colonisation: Antenatal/Intrapartum Strategies to Prevent Early-Onset Sepsis in Neonates (clinical algorithim)

Notes


Active population based surveillance has shown that such strategies have decreased early onset neonatal sepsis by up to 70%.

In elective Caesarean sections (not in labour; no rupture of membranes) no prophylaxis is recommended, irrespective of carriage. [Level C11]

Adequate intrapartum chemoprophylaxis is defined as penicillin > or = to 4 hours prior to delivery. [Level C11]

Any woman with a previous GBS infected (not just colonized) baby should have antimicrobial chemoprophylaxis in subsequent pregnancies, irrespective of her colonisation status. [Level B11]

Swab Collection


View the patient instruction sheet: Swab Collection


Royal Women's Hospital Clinical Practice Guidelines (CPGs) are intended to provide guidance to health care professionals, based on a thorough evaluation of research evidence, on the practical assessment and management of specific clinical issues or situations. The guidelines allow some flexibility on the part of the health care professional based on the needs of the specific patient for whom they are caring.

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